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2,2,2-Trifluoroethylamine

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Keywords: Difluoroethanol/ N-Methylpyrrolidone

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Product Details

2,2,2-Trifluoroethylamine is an important organic compound, and the following is its detailed information:

Basic Information Chemical formula: C2H4F3N

Molecular weight: 99.06

CAS Registry Number: 753 - 90 - 2

EINECS Registry Number: 212 - 041 - 3

Physical and Chemical Properties

Appearance and properties: Transparent colorless liquid.

Density: 1.262 g/mL (at 20°C)

Melting point: -107°C

Boiling point: 36 - 37°C

Flash point: -16°C

Refractive index: 1.301 (at 20°C)

Solubility: Slightly soluble in water, miscible with organic solvents such as ethanol and diethyl ether.

Molecular Structure Data

Molar refraction: 15.30

Molar volume: 81.6 m3/mol

Isotactic specific volume: 164.3

Surface tension: 16.4 dyne/cm

Polarizability: 6.06

Applications As a pharmaceutical intermediate: It is used to synthesize a variety of drugs, such as preparing 1,2-substituted guanidine and its derivatives, which can be used to treat diseases such as diabetes; it can also be used to prepare bis-substituted aniline derivatives for the treatment of diseases of the central nervous system and cardiovascular system. As a pesticide intermediate: It can be used to synthesize pesticides with good activity, such as insecticides, acaricides, ovicides, fungicides, herbicides, etc. As a catalyst: As a weakly basic amine catalyst, it can catalyze the removal of the α-proton in the reaction by forming an ammonium ion; it can also catalyze reactions such as the hydration of diketene and the isomerization of ketene. Other applications: It is used to prepare 2,2,2-trifluoroethanol; it undergoes electrooxidative condensation with diaryl disulfides to prepare N-(2,2,2-trifluoroethyl)-sulfonamide, which is used to synthesize trifluoromethylamine, aminoketones, and aminoalkanoates, etc.

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2,2,2 - trifluoroethylamine hydrochloride

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2,2,2 - trifluoroethylamine hydrochloride

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