Introduction of trifluoroacetaldehyde hydrate

Today there are still many people who do not understand some basic information about trifluoroacetaldehyde hydrate, so as a manufacturer, we also need to briefly explain, in fact, this trifluoroacetaldehyde hydrate is everywhere we can see the existence of its unique structure, in the industrial field is also playing a very important role, so we have to timely to understand its principle structure, so that in operation can be more quickly familiar with and use.

Trifluoroacetaldehyde hydrate, 2,2,2-trifluoroacetaldehyde molecular formula C2HF30, CAS registration number 75-90-1, molecular weight 98.02, colorless gas in normal state, boiling point -18.8 ℃. Trifluoroacetaldehyde is unstable, easily polymerised and rapidly absorbed by water or ethanol to produce stable trifluoroacetaldehyde hydrate or trifluoroacetaldehyde semi-ethanol acetal. Trifluoroacetaldehyde and its derivatives are important reagents for trifluoromethylation and are widely used in synthetic resins, polymers, rubber, coatings, pharmaceuticals and pesticides.

Trifluoroacetaldehyde hydrate can synthesise a variety of heterocyclic compounds containing trifluoromethyl groups. These compounds are mainly used in the production of pesticides and dyes. For example, trifluoroacetaldehyde can be used to prepare reactive lactones via the Reformasky reaction. Trifluoroacetaldehyde can be used to prepare fluorine or trifluoromethyl pyrazoles, tetrahydropyrans and oxazolidine heterocyclic compounds via cycloaddition reactions or bi-nuclear reagent reactions; Wittig reactions of trifluoroacetaldehyde produce trifluoroacetaldehyde, etc. The above compounds are mainly used in the synthetic resin, rubber, coating, pharmaceutical and pesticide industries as research progresses. The areas of use will continue to expand in the future. Trifluoroacetaldehyde hydrate should be solid and transparent crystals, but it is not easy to store and absorbs moisture easily. Water absorption becomes a liquid, or a mixture of liquid and solid. However, chloral hydrate can also be used in liquid form, or as a mixture of liquid and solid, and will not fail. It is still used in the laboratory, but not if the proportions of the prepared solution are very strict, as it contains a certain amount of water and cannot be taken accurately. To avoid problems caused by polymerisation and auto-oxidation, liquid solutions of trifluoroacetaldehyde hydrate should be refrigerated and used immediately after preparation. However, trifluoroacetaldehyde hydrate is carcinogenic and direct contact is to be avoided. The reagent is hygroscopic and sensitive to air and moisture and needs to be used in an evaporator.

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