Product Description
2,2,2-Trifluoroethylamine is an important organic compound, and the following is its detailed information:
Basic Information Chemical formula: C2H4F3N
Molecular weight: 99.06
CAS Registry Number: 753 - 90 - 2
EINECS Registry Number: 212 - 041 - 3
Physical and Chemical Properties
Appearance and properties: Transparent colorless liquid.
Density: 1.262 g/mL (at 20°C)
Melting point: -107°C
Boiling point: 36 - 37°C
Flash point: -16°C
Refractive index: 1.301 (at 20°C)
Solubility: Slightly soluble in water, miscible with organic solvents such as ethanol and diethyl ether.
Molecular Structure Data
Molar refraction: 15.30
Molar volume: 81.6 m3/mol
Isotactic specific volume: 164.3
Surface tension: 16.4 dyne/cm
Polarizability: 6.06
Applications As a pharmaceutical intermediate: It is used to synthesize a variety of drugs, such as preparing 1,2-substituted guanidine and its derivatives, which can be used to treat diseases such as diabetes; it can also be used to prepare bis-substituted aniline derivatives for the treatment of diseases of the central nervous system and cardiovascular system. As a pesticide intermediate: It can be used to synthesize pesticides with good activity, such as insecticides, acaricides, ovicides, fungicides, herbicides, etc. As a catalyst: As a weakly basic amine catalyst, it can catalyze the removal of the α-proton in the reaction by forming an ammonium ion; it can also catalyze reactions such as the hydration of diketene and the isomerization of ketene. Other applications: It is used to prepare 2,2,2-trifluoroethanol; it undergoes electrooxidative condensation with diaryl disulfides to prepare N-(2,2,2-trifluoroethyl)-sulfonamide, which is used to synthesize trifluoromethylamine, aminoketones, and aminoalkanoates, etc.
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